Adaptive designs based on the truncated product method
نویسندگان
چکیده
منابع مشابه
Adaptive designs based on the truncated product method
BACKGROUND Adaptive designs are becoming increasingly important in clinical research. One approach subdivides the study into several (two or more) stages and combines the p-values of the different stages using Fisher's combination test. METHODS Alternatively to Fisher's test, the recently proposed truncated product method (TPM) can be applied to combine the p-values. The TPM uses the product ...
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ژورنال
عنوان ژورنال: BMC Medical Research Methodology
سال: 2005
ISSN: 1471-2288
DOI: 10.1186/1471-2288-5-30